DrAutoimmuneGirl | Donna Mazzola

A huge component to this is reducing inflammation and there are several ways to do that through diet and lifestyle- especially stress reduction. _ But there are several measures that have been studied that impact antibodies. _ Lets break it down: 📌​GLUTEN FREE DIET: The gluten-free diet may also directly inhibit activity of inflammatory cells. Research has found that the gluten-free diet reduced serum titers of TPOAb and TGAb in euthyroid women with Hashimoto’s thyroiditis. (PMID: 30060266) 📌​SELENIUM: A 2016 systematic review and meta-analysis by Wichman et al. showed that Se supplementation effectively reduces serum TPO-Ab levels at 3, 6, and 12 months and serum Tg-Ab at 12 months. Brazil nuts are a great source. 📌​ALOE: Aloe vera juice rescues thyroid hormone production by reducing inflammation in the thyroid gland and reducing the need for conversion of T4 into T3. A study that had women take 50mL of Aloe found reduction in TPOAb Baseline: 1,020 to TPOAb 9 Months: 347. (PMID: 29527506) 📌​VITAMIN D: A study observed that increased prevalence of Vitamin D deficiency and insufficiency in thyroid peroxidase antibody (TPO-Ab) or thyroglobulin antibody (TgAb) positive patients when compared to those with negative antibody status. A cross-sectional study documented increased the prevalence of TPO-Ab positivity in women with Vitamin D deficiency and insufficiency as compared to Vitamin D sufficient persons. (PMID: 28163731) 📌Turmeric: The active constituent curcumin can suppress NF-kB, the king of inflammatory pathways and considered a key player in altered immune response and chronic inflammation. Personally I put this in my smoothies to reduce overall inflammation! _ Please share your experiences in the comment, let’s get the conversation started on what has worked for you! Check out my vitD and Aloe @besananutrition _ #hashimotosdisease #hashimotos #hashimoto #hashimotosthyroiditis #hashimotoswarrior #hashimotoshealing #hashimotosthyroiditis #hashimotosmom #thyroidhealing #thyroid #thyroidproblems #thyroidhealth #thyroiddisease #thyroidwarrior #thyroidsupport #thyroidissues #thyroidawareness

Estrogen appears to push the immune system in the direction of the proinflammatory Th1 pathways, EXCEPT during pregnancy. Because pregnancy is actually a high-estriol/high-progesterone state, estriol, functionally a weak estrogen and progesterone clearly has anti-estrogen properties - we actually see an improvement because estrogen levels are actually low. This is the potential reason why autoimmune diseases that involve over-expression of Th1 (e.g., rheumatoid arthritis, multiple sclerosis) frequently “go away” during pregnancy but “come back” during postpartum periods. Thus, pregnancy appears to represent a unique situation for the immune system, switching from a Th1-dominant environment to an often Th2-dominant environment. Full Blog post on Drautoimmunegirl.com - Check it out for all the deets! #autoimmunedisease #autoimmuneprotocol #autoimmunepaleo #pregnancylife

I made these every Sunday for over a year and it’s what helped me get past my egg allergy… now I continue to make them every Sunday with my overripe bananas! Recipe: 2 cups oatmeal 60 grams dates 74 grams orgain protein powder (40 grams protein) 2 eggs 5 ounces siggis plant based protein yogurt (vanilla) 2 ripe bananas 1/2 cup almond milk 1 tsp vanilla 1 tsp salt 1 tsp cinnamon 1 tsp baking soda Blend in food processor for 2.5 minutes Put muffin liners in pan scoop 1/4 cup in each and add 4 blueberries to each and mix Bake at 350 for 25 minutes MACROS: 24 g carbs, 5g fat, 9 G protein

Many studies have indicated that alterations in the gut microbiota are important environmental factors in the development of inflammatory and autoimmune diseases.⠀⠀⠀⠀⠀⠀⠀⠀⠀ __⠀⠀⠀⠀⠀⠀⠀⠀⠀ A comparative analysis looked at gut microbiota in Hashimotos patients and healthy controls… WHAT DID THEY FIND?⠀⠀⠀⠀⠀⠀⠀⠀⠀ __⠀⠀⠀⠀⠀⠀⠀⠀⠀ Levels of Fecalibacterium, Bacteroides, Prevotella were decreased. ⠀⠀⠀⠀⠀⠀⠀⠀⠀ __⠀⠀⠀⠀⠀⠀⠀⠀⠀ TRANSLATION: WHAT DO THESE DEFICIENCIES CORRELATE TO???⠀⠀⠀⠀⠀⠀⠀⠀⠀ __⠀⠀⠀⠀⠀⠀⠀⠀⠀ FACALIBACTERIUM: produce butyrate, which is essential for energy metabolism and the normal development of colonic epithelial cells. Other studies have shown that it has an anti-inflammatory effect⠀⠀⠀⠀⠀⠀⠀⠀⠀ __⠀⠀⠀⠀⠀⠀⠀⠀⠀ PREVOTELLA: are also known to produce anti-inflammatory metabolites, ALSO decreased levels have been reported in diseases such as #MultipleSclerosis , #autism, and #T1D⠀⠀⠀⠀⠀⠀⠀⠀⠀ __⠀⠀⠀⠀⠀⠀⠀⠀⠀ BACTEROIDES: ferment fiber into acetates and propionates producing short-chain fatty acids, which are intestinal nutrients that protect the intestinal mucosal barrier and reduce inflammation⠀⠀⠀⠀⠀⠀⠀⠀⠀ __⠀⠀⠀⠀⠀⠀⠀⠀⠀ OVERALL, the changes in gut microbial structure are similar between #IBS and Hashimotos patients⠀⠀⠀⠀⠀⠀⠀⠀⠀ …⠀⠀⠀⠀⠀⠀⠀⠀⠀ These findings are consistent with those of a previous study that reported significant increases in Firmicutes and decreases in Bacteroidetes species in obese, IBS, and MS patient⠀⠀⠀⠀⠀⠀⠀⠀⠀ —⠀⠀⠀⠀⠀⠀⠀⠀⠀ Studies have indicated that microflora of IBS patients has a higher F/B ratio. Therefore, it is thought that an increased F/B ratio corresponds to HT disease status⠀⠀⠀⠀⠀⠀⠀⠀⠀ __⠀⠀⠀⠀⠀⠀⠀⠀⠀ There is just still so much we don’t know about the gut microbiota, but it definitely gives hope! Your gut is everything, especially with autoimmune disorders. This is why I created my PIRH protocol and gut bundle from @besananutrition Share your Thoughts and experience????⠀⠀⠀⠀⠀⠀⠀⠀⠀ …⠀⠀⠀⠀⠀⠀⠀⠀⠀ #hashimotosdisease #hashimotos #hashimoto #hashimotosthyroiditis #hashimotoswarrior #hashimotoshealing #hashimotosthyroiditis #hashimotosmom #thyroidhealing #thyroid #thyroidproblems #thyroidhealth #thyroiddisease #thyroidwarrior #autoimmune #autoimmunedisease #guthealth #leakygut #guthealth

✅Immune Response: 🌀Food Allergy: Involves the immune system producing Immunoglobulin E (IgE) antibodies upon exposure to the allergen, leading to the release of chemicals like histamines and leukotrienes. 🌀Food Intolerance: Results from incomplete digestion or metabolism of a food, with symptoms resembling those of irritable bowel syndrome (IBS). ✅Symptoms: 🌀Food Allergy: Symptoms can range from mild to severe, involving immediate reactions such as hives, swelling, and even anaphylaxis. 🌀Food Intolerance: Symptoms typically include gas, bloating, nausea, and diarrhea, resembling digestive issues. ✅Testing: 🌀Food Allergy: Objective tests, including skin prick tests or blood tests measuring IgE antibodies, can help diagnose true allergies. 🌀Food Intolerance: No immunologically based objective tests exist. Some labs use IgG testing, but its reliability is debated. ✅Mechanism (IgG-Mediated): 🌀Food Allergy: IgE-mediated immune response involving mast cells. 🌀Food Intolerance: IgG-mediated intolerance, often associated with increased gut permeability (leaky gut), allowing food substances to trigger IgG production. ✅Prevalence: 🌀Food Allergy: Generally less common, and the likelihood of developing a new allergy in adulthood is slim. 🌀Food Intolerance: Estimated prevalence is 5-20% of the general population, though true prevalence is uncertain. ✅Treatment and Tolerance: 🌀Food Allergy: Strict avoidance of the allergen is crucial, as exposure can lead to severe reactions. 🌀Food Intolerance: Building tolerance may be possible through an elimination diet, followed by a gradual reintroduction of foods without symptom reproduction. ✔️Takeaway: • 🔘The likelihood of developing a new food allergy in adulthood is rare. • 🔘For IBS-related symptoms, cautious consideration of IgG testing is recommended, and an elimination diet followed by gradual reintroduction is often a gold standard. • 🔘Quality, organic, GMO-free foods can contribute to overall gut health and potentially prevent intolerances. Link in bio!

Aloe vera rescues thyroid hormone production by reducing inflammation in the thyroid gland and reducing the need for conversion of T4 into T3- that’s the conclusion of a 9 month study on aloe and hashimotos. PMID: 29527506 I’m always intrigued by mechanisms to reduce antibodies! This study is super interesting and was actually triggered because one of the authors noticed a significant improvement in her numbers after she started taking aloe vera as a laxative! As a result this study protocol was developed! She noticed that after drinking aloe juice for 3 and 6 months, her TSH, Free T4, Free T3, and thyroid peroxidase antibodies (TPOAb) all improved. Her TSH went from 5.14 to 1.83. Free T4 improved from 8.3 to 11.44. Free T3 went from 5.22 to 4.78 which indicates improved efficiency. And TPOAb decreased from 1,875 to 246. These were quite profound changes with no other interventions and no thyroid medication. I developed Aloe Bacterial Balance as a one stop shop to aid in multiple levels of healing. Thyroid Support and reducing antibodies is just one of them! Product tagged!! Check it out at drautoimmunegirl.com Anyone have a positive experience they want to share? _ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ #hashimotosdisease #hashimotos #hashimoto #hashimotosthyroiditis #hashimotoswarrior #hashimotoshealing #hashimotosthyroiditis #hashimotosmom #thyroidhealing #thyroid #thyroidproblems #thyroidhealth #thyroiddisease #thyroidwarrior #thyroidsupport #thyroidissues #aloevera #aloeveraplant #aloevergel #aloeverajuice #aloeveradrink

I’ve been asked by so many what’s the correlation between thyroid dysfunction and infertility. _ Thyroid dysfunction can impact fertility in a few different ways, from ovulation to hormone imbalances to high prolactin levels. _ Thyroid function should be checked in anyone who is trying to get pregnant and has had multiple miscarriages, has irregular cycles, or has a family history of thyroid problems. _ A workup should be a complete panel checked TSH,T3,T4 and TPO antibodies _ It’s estimated that TPO antibodies doubles the risk of recurrent miscarriages in women with otherwise normal thyroid function _ In a study that enrolled 394 women with infertility found that almost 20% of the women had raised TSH levels and high prolactin. _ Of those women with high TSH 63% were subclinical with TSH 4–6 μIU/ml _ I’m making a point to focus on those that are subclinical because sometimes this can be ignored by clinicians as “normal” _ Of the 94 infertile women diagnosed with hypothyroidism (76.6%) conceived after treatment with drugs for hypothyroidism (dose depending upon severity of hypothyroidism, i.e. TSH levels). _ 62.5% women conceived after 6 weeks to 3 months of therapy 37.5% women conceived after 3 months to 1 year of therapy _ This study supports the fact that TSH levels in the narrower range or borderline cases, i.e. 4–5, 5–6, and >6.0 μIU/ml, should not be ignored in infertile women which are otherwise asymptomatic for clinical hypothyroidism (PMID: 23776802) _ Please share your experience with me if you can relate. I know fertility is multifaceted, but thyroid dysfunction is one area that should be certainly considered. _ After finding this out through my own experience, I feel it should be a standard screening for ANYONE that is trying to conceive. _ Thoughts? #fertility #infertility #ivf #fertilityjourney #pregnancy #ivfjourney #pcos #fertilityawareness #infertilityawareness #endometriosis #womenshealth #health #fertilitytreatment #baby #pregnant #ttcsupport #ivfsuccess #fertilitysupport #infertilitysucks #tryingtoconceive #infertilitysupport #miscarriage #ivfsupport #thyroid #hashimotos #hashimotosdisease #hypothyroidism #hypothyroidmom

Whoa!! That number is high. Let’s understand what SIBO is and the connection with hypothyroidism SIBO is an acronym for Small Intestinal Bacterial Overgrowth—> well the first thing you should know about that is there shouldn’t be any bacteria let alone overgrowth in the small intestine The bacteria in our gut should be housed in the large intestine and stay out of the small intestine The main symptom that most complain about is bloating…. Bloating so severe you look pregnant- well at least that was me!! My family thought I was faking it when I showed them my stomach. NO WAY!! What happens is that bacteria in the small intestine ferment the foods you eat and create either hydrogen or methane gas (I’ll talk about that in a future post) So what can cause or contribute to SIBO? Well its basically the inability to break down food or food sitting too long. Low stomach acid, low digestive enzymes, slow gut transit or food poisoning. We know with HYPOthyroidism, everything slows down and this includes gut transit, giving bacteria the opportunity to take on the small intestine. What’s key here is also recognizing this can impact the absorption of key nutrients like B12 and iron. So when my iron was chronically low even when I took supplements I knew I had to dig deeper to better understand why. Post treatment my levels have normalized WITHOUT the need for supplementation! Stool testing demonstrated the presence of particular bacteria that are known to produce methane and hydrogen gas, but a SIBO breathe test confirmed it I took BOTH the antibiotic and herbal route! This is my experience and my story. I share with you to raise awareness and give you the knowledge to ask the right questions. Who else has experienced SIBO? #functionalmedicine #guthealthmatters #hormonebalance #holisticnutrition #sibo #sibodiet #fodmapfriendly #preventativemedicine #goodguthealth #guthealthisreal #healthygut #guthealthy #nutritiousanddelicious #fuelyourbody #holistichealth #nourishyourbody #guthealth #guthealthyfood #guthealthdiet #guthealthiskey #guthealthiseverything #hypothyroidism #hypothyroidismsupport #hashimotos #hashimoto